Drug Index


Mechanism :

It is a muscle-relaxant. It acts by inhibiting muscle spasms by acting at the level of the spinal cord and subcortical areas of the brain. It is used as a skeletal muscle relaxant.

Indication :

  • Musculoskeletal pain and muscle spasms

Contraindications :

Hypersensitivity, Impaired liver function.

Dosing :

2.5-7.5 mg/kg/dose PO 3-4 times per day.
Max: 750 mg/dose.

Adverse Effect :

Light headedness, dizziness, drowsiness, excitement, paradoxical somnolence, malaise, rash angioneurotic edema, gastrointestinal hemorrhage (rare), hepatotoxicity (rare), anaphylaxis (rare).

Interaction :

Doxylamine: Combo may increase risk of CNS depression, psychomotor impairment (additive effects).
Sodium oxybate: May increase risk of CNS depression, psychomotor impairment, adverse effects (additive effects).

Hepatic Dose :

Use is contraindicated in children with hepatic impairment. Chlorzoxazone has been associated with idiosyncratic and fatal hepatotoxicity.
02/22/2024 12:36:48 Chlorzoxazone
Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0