Drug Index

Carbamide

 
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Mechanism :

Carbamide peroxide, also called urea peroxide, is an oxidising agent, consisting of hydrogen peroxide compounded with urea.


Indication :

• Teeth whitening

• Canker sores or gum irritation

• Ear wax removal


Contraindications :

Hypersensitivity.


Dosing :

Use in children >2 years.

Canker sores or gum irritation:

Apply several drops to affected area, expectorate out after 2-3 minutes, OR

Place 10 drops on tongue, mix with saliva, swish in mouth for several minutes, then expectorate. May repeat up to 4 times/day.

Oral hygiene:

15% liquid: Apply to toothbrush, cover with toothpaste, brush & expectorate.

Ear wax removal: Available as otic 6.5% solution:

1 to 5 drops twice daily for up to 4 days (Max: 10 drops twice daily); individualize the dose according to patient size.


Adverse Effect :

The chemical is a skin, eye and respiratory irritant. It is also corrosive and causes burns. It doesn’t hurt at 10% concentration (3% peroxide equivalent) but it does hurt at 35% equivalent, causing white chemical burns on skin and gums alike.


Interaction :

With allogeneic cultured keratinocytes/fibroblasts in in bovine collagen: Decreases the effect of allogeneic cultured keratinocytes/fibroblasts in in bovine collagen.


07/14/2019 19:38:44 Carbamide
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