Drug Index


Mechanism :

Dextran produces plasma volume expansion due to increased colloid pressure, it draws interstitial fluid into intravascular space.

Indication :

  • Fluid replacement in shock

Contraindications :

Known hypersensitivity to dextran, severe CHF, renal failure, severe thrombocytopenia, severe bleeding disorders.

Dosing :

Start with 10 ml/kg rapid intravenous infusion not more than 20 ml/kg in first 24 hours, and not more than 10 ml/kg thereafter, total treatment not more than 5 days.

Adverse Effect :

Nausea, vomiting, hypotension, fever, urticaria, arthralgia, pulmonary edema

Interaction :

Falsely elevates serum glucose and faulty serum bilirubin assays.

Hepatic Dose :

Use with extreme caution.
03/20/2024 21:10:41 Dextran
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