Drug Index

Pentoxifylline

 
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Mechanism :

It is a peripheral vasodilator used in the treatment of peripheral vascular disease (Raynaud’s disease).
It may be useful in lowering blood sugar level, also reduces blood pressure.


Indication :

• Intermittent claudication in certain patients to reduce pain, cramping, numbness, or weakness in the arms or legs.

• For patients with Kawasaki disease to reduce the incidence of coronary artery lesions


Contraindications :

Methylxanthine intolerance, Recent cerebral hemorrhage, Recent retinal hemorrhage.


Dosing :

Safety and efficacy have not been established in children.

Limited off-label data indicate 20 mg/kg/day PO in 3 divided doses.


Adverse Effect :

Arrhythmias, hypersensitivity reaction, dyspepsia, nausea.


Interaction :

Aspirin: Combining these medications may occasionally increase the risk of bleeding. Tamsulosin: Pentoxifylline may enhance the blood pressure lowering effects of tamsulosin. You may experience headache, dizziness, light-headedness, fainting, and/or changes in pulse or heart rate.


07/14/2019 19:36:51 Pentoxifylline
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