Citrulline
Mechanism :
Citrulline is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle.
Indication :
- Lysinuric protein intolerance
- Carbamoyl phosphate synthetase (CPS)
- Ornithine carbamoyl transferase (OCT) deficiency
Contraindications :
Citrulline is contraindicated in conditions like Pregnancy, Liver damage, Kidney infection, Breast feeding, Hypersensitivity to any component of product.
Dosing :
42.5 mg/kg/dose 4 times daily.
Adverse Effect :
Transient gastric pain.
Interaction :
No known interactions found.
Hepatic Dose :
No dosage adjustments are recommended.