Biotin
Mechanism :
Biotin, also known as vitamin H or B 7, is a water-soluble B-complex vitamin.
Indication :
- Propionic acidemia
- Biotinidase deficiency
- Holocarboxylase synthetase deficiency
Contraindications :
Hypersensitivity to biotin or any of its components.
Dosing :
Daily Dietary Requirements:
Infants; 0-1 year: 5-6 mcg/day.
Children; 1-9 years: 8-12 mcg/day.
Adolescents; 9-18 years: 20-25 mcg/day.
For Biotinidase deficiency:
10-20 mg/day (Oral) in two divided doses.
Adverse Effect :
Hypersensitivity to biotin or any of its components.
It is generally safe.
Hepatic Dose :
No dosage adjustments are recommended.