Clobetasone
Mechanism :
It is a glucocorticoid with anti-inflammatory properties. It is used as a topical agent for reducing local inflammation of skin in diseases like eczema, psoriasis, lichen planus, contact and seborrheic dermatitis.
Indication :
- Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Contraindications :
Underlying infection, Hypersensitivity, Ophthalmic use.
Dosing :
Available as 0.05%/15 gm cream.
Apply thin layer to affected areas q12hr (not to exceed 50 g/week).
Adverse Effect :
Systemic adrenal suppression (subcapsular cataract, osteoporosis, glaucoma, peptic ulcers and adrenal suppression), skin atrophy.
Interaction :
No significant interactions known or found for this drug.
Hepatic Dose :
No dosage adjustments are recommended.