Drug Index

Metaxalone

 
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Mechanism :

Metaxalone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain.


Indication :

• Muscle spasm

• Systemic sclerosis

• Cardiac allograft rejection


Contraindications :

Hypersensitivity to drug/class/component, Anaemia.


Dosing :

Muscle spasm: 12 years or above: 800 mg orally for 3 to 4 times a day. Give on empty stomach.


Adverse Effect :

Common Reactions: Drowsiness, somnolence, dizziness, headache, nervousness, nausea, vomiting, dyspepsia.

Serious Reactions: Hemolytic anemia, leukopenia, anaphylaxis.


Interaction :

Triprolidine: The CNS depressants, Triprolidine and Metaxalone, may increase adverse/toxic effects due to additivity. Monitor for increased CNS depressant effects during concomitant therapy.


07/14/2019 19:27:00 Metaxalone
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