Drug Index

Teicoplanin

 
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Mechanism :

It is an antibiotic that acts against coagulase producing Gram-positive cocci. It is used in the treatment of endocarditis, peritonitis, septicemia, osteoarthritis.


Indication :

• Severe Gram-positive infections


Contraindications :

Hypersensitivity.


Dosing :

Initial: 10 mg/kg/dose every 12 hours for 3 doses IV and then 6 mg/kg/day IV/IM 24 hourly.

Neonates: Initial dose is 16 mg/kg and maintenance dose is 8 mg/kg/day IV. Infuse over 30 mins.


Adverse Effect :

Fever, chills, allergic reactions, GI disturbances, headache, dizziness, “red-man” syndrome, disturbances in liver enzymes, renal impairment, ototoxicity, blood dyscrasias, erythema and thrombophlebitis at site of administration.

Rare: Stevens-Johnson syndrome, toxic epidermal necrolysis.


Interaction :

Other nephrotoxic and/or neurotoxic drugs.


07/15/2019 05:46:40 Teicoplanin
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