Drug Index


Mechanism :

N-carbamylglutamate (NCG), an analogue of endogenous N-acetylglutamate which is an activator of arginine synthesis.

Indication :

  • N-acetyl glutamate synthase (NAGS) deficiency
  • Carbamoyl phosphate synthase deficiency

Contraindications :

No significant contraindications found.

Dosing :

12.5-25 mg/kg/dose QDS.

Adverse Effect :

Chinese restaurant syndrome characterized as a sympathomimetic reaction including tachycardia, profuse sweating, increased bronchial secretion and temperature, and persistent crying.

Interaction :

No significant interactions found.

Hepatic Dose :

No dosage adjustments are recommended.
01/20/2024 15:31:26 Carbamylglutamate
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