Drug Index

Chlorhexidine Gluconate

 
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Mechanism :

Chlorhexidine gluconate is active against a broad spectrum of microbes. The chlorhexidine molecule, due to its positive charge, reacts with the microbial cell surface, destroys the integrity of the cell membrane, penetrates the cell, precipitates the cytoplasm, killing the cell.


Indication :

• Sialadenitis

• Dental plaques

• Aphthous ulcer

• Mucositis

• Gingivitis prevention

• Post-operative mouth antiseptic


Contraindications :

Chlorhexidine should not be used in any patient who has a known sensitivity to chlorhexidine.


Dosing :

Dental gel: 1 inch of gel brushed around the teeth and gums once or twice daily for 1 minute. Apply for 1 month for gingivitis.

Mouth wash: 0.12% 15 ml for 30 seconds BDS.

Oral spray: Up to 12 actuations-to be used twice daily. For the prevention of gingivitis, use for 1 month. In aphthous ulcer and oral infections, use for 48 hours after the infection has cleared.


Adverse Effect :

Toothache, headache.


Interaction :

No known drug interactions found.


07/17/2019 20:51:09 Chlorhexidine Gluconate
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