Drug Index

Dextran

 
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Mechanism :

Dextran produces plasma volume expansion due to increased colloid pressure, it draws interstitial fluid into intravascular space.


Indication :

• Fluid replacement in shock


Contraindications :

Known hypersensitivity to dextran, severe CHF, renal failure, severe thrombocytopenia, severe bleeding disorders.


Dosing :

Start with 10 ml/kg rapid intravenous infusion not more than 20 ml/kg in first 24 hours, and not more than 10 ml/kg thereafter, total treatment not more than 5 days.


Adverse Effect :

Nausea, vomiting, hypotension, fever, urticaria, arthralgia, pulmonary edema


Interaction :

Falsely elevates serum glucose and faulty serum bilirubin assays.


07/17/2019 10:46:56 Dextran
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