Question of the Week

Question :
Posted On : 03 Sep 2023
A one and a half year old female child presented with seizures that were generalized tonic in nature lasting for about 2-3 minutes not followed by any post ictal events or loss of consciousness. CT, EEG and MRI were done. All were inconclusive. She continued to have seizures in spite of antiepileptic. She was neurologically normal with normal birth history and no history of any head injury. Lab parameters were normal (Calcium, phosphorus, sodium, potassium, chloride). She had multiple hyopigmented patch over her both lower limbs. What is the diagnosis and whether it was prudent in treating her seizures? Was it a case of resistant seizures?
5
Expert Answer :
In true epileptic seizures, there should be some alteration of consciousness if the patient is jerking all four limbs. Hypopigmented patches are seen in Tuberous Sclerosis (MRI should have shown tubers), hypomelanosis of Ito{ usually developmental delay}. If patches are vitiliginous consider an autoimmune workup. An unusual cause of refractory seizures in previously normal children is Anti-NMDA encephalitis.
Answer Discussion :
A
Ahmed
Profile
Tuberous sclerosis
9 months ago
S
Sanjae-Ann Dean
Profile
Neurocutaneous syndrome - TSC or NF1
9 months ago
A
Ali Ali
Profile
tuberosclerosis
9 months ago
G
Gladys Yonah
Profile
lesions are cafe au lait, suggesting a neurological error, probably inborn error of metabolism
9 months ago
C
Candice Bair
Profile
TSC with possibility if traveled recently Lyme disease can cause the following symptoms as well
9 months ago




Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The site does not guarantee the accuracy or authenticity of the information. Use of any information is solely at the user's own risk. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer.
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0