Novel Influenza A (H1N1) Laboratory Testing

Abhay Chowdhary
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Novel Influenza A (H1N1) Laboratory Testing - Introduction
Human cases of novel influenza A (H1N1) virus infection have been confirmed in people all over the world. WHO declared the pandemic Investigations of these cases suggest that on-going human-to-human novel H1N1 virus is occurring. Illness signs and symptoms have consisted of fever and respiratory tract illness (cough, sore throat, runny nose), headache, muscle aches, Some cases have had vomiting and diarrhea. Cases of severe respiratory disease, including fatal outcomes, have been reported.

The novel H1N1 virus that has infected humans all over the world is a novel influenza A virus that is resistant to the antiviral medications amantadine and rimantadine but is sensitive to oseltamivir and zanamivir.

A confirmed case of novel influenza A (H1N1) virus infection is defined as a person with an influenza-like illness with laboratory confirmed novel influenza A (H1N1) virus infection by one or more of the following tests:1. real-time RT-PCR 2. viral culture.

The duration of shedding with novel influenza A (H1N1) virus is unknown. Therefore, until data are available, the estimated duration of viral shedding is based upon seasonal influenza virus infection. Infected persons are assumed to be shedding virus and potentially infectious from the day prior to illness onset until resolution of fever. Infected persons should be assumed to be contagious up to 7 days from illness onset. Some persons who are infected might potentially shed virus and be contagious for longer periods (e.g. young infants, immunosuppressed, and immunocompromised persons).


Novel Influenza A (H1N1) Laboratory Testing Novel Influenza A (H1N1) Laboratory Testing 01/06/2009
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