Scrub Typhus

Ira Shah
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Scrub Typhus - Diagnosis
The Weil-Felix OX-K strain agglutination reaction may be the only serologic test available in less developed countries. However, it is not very sensitive; OX-K agglutinins develop in only a little more than 50 percent of scrub typhus patients. Moreover, OX-K agglutinins are also produced by relapsing fever. A fourfold rise in agglutinin titres in paired sera, or a high cut-off titre (>1:320) in single samples are diagnostic for skin infection. Immunofluorescent tests are much more diagnostic and reliable.


References
Scrub Typhus Scrub Typhus 01/02/2013
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